A much better alternative, especially for older people and those on steroids, when the stomach side effects ( indigestion, heart burn, bleeding) of NSAIDs can be a real problem.
The multi-center trial was
conducted with 109 patients with primary knee osteoarthritis who were
randomized to receive either ibuprofen 800 mg day ibuprofen (55 patients) or
2,000 mg turmeric per day (52 patients), for 6 weeks. The ibuprofen was
divided into 2 doses of 400mg daily, and the turmeric into 4 doses of 500 mg
daily.
The researchers measured pain on level walking,
pain on stairs, and functions of knee assessed by time spent during 100-m walk
and going up and down a flight of stairs, as the primary outcomes.
After six weeks, significant improvements were
observed in both groups, with all primary outcomes similar, except the turmeric group showed
slightly better performance on the 100-m walk and less self-reported pain going
up and down a flight of stairs. Also, the turmeric group showed less
adverse events. Also, the subjects rated themselves to have higher
satisfaction with the treatment results in the turmeric group (91.1%) versus
the ibuprofen group (80.4%).
Efficacy and safety of Curcuma
domestica extracts compared with ibuprofen in patients with knee
osteoarthritis: a multicenter study. Clin Interv Aging. 2014 ;9:451-8. Epub 2014 Mar 20. PMID: 24672232
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